M.D. Physiology

P.G. Curriculum

M.D. Physiology Index

 

 

  1. Goal
  2. Objectives
  3. Syllabus 
  4. Teaching Program
  5. Posting
  6. Thesis
  7. Assessment
  8. Job Responsibilities
  9. Suggested books
  10. Model Test Papers  

Curriculum

M.D. Physiology

 

 

The infrastructure and faculty of the department of Physiology will be as per MCI guidelines.

 

1. Goals  

The goal of MD Course in Physiology is to produce a competent physiologist who:

 

  •  Is able to demonstrate comprehensive understanding of physiology as well as that of applied disciplines;
  •  Is able to demonstrate adequate knowledge of the current developments in medical sciences as related to physiology;
  •  Has acquired skills in effective teaching and communicating with medical and paramedical students;
  •  Is oriented to principles of research methodology and is thus able to plan and conduct research effectively;
  •  Is able to plan educational programmes in physiology utilizing modern methods of teaching and evaluation;
  •  Is able to organize and equip physiology labs. 

 

2. Objectives

At the end of MD Course in Physiology, the student should be able to :

  •  Demonstrate comprehensive understanding of the structure, functions and development of human body as related to physiology, all the factors which might disturb these, mechanisms of such disturbances and the disorders of structure and function;
  •  Critically evaluate the impact of recent information on the genesis of current concepts related to various topics of physiology;
  •  Recapitulate the information imparted to the UG students in physiology;
  •  Perform and critically evaluate the practical exercises done by UG students;
  •  Demonstrate competence in basic concepts of research methodology,   effectively use the statistical methods and write a scientific paper on the lines accepted by standard scientific journals;
  •  Design, fabricate and use indigenous gadgets for experimental purposes;   Demonstrate familiarity with the principles of medical education;
  •  Draw out meaningful curricula for teaching medical and paramedical courses;
  •  Organize the labs for various practical exercises, substitute and fabricate some of the simpler
  • quipment for teaching purposes;
  •  Handle and order for stores, draw up lists of equipment required to equip physiology labs;
  •  Develop skills as a self directed learner, recognize continuing educational needs; use appropriate learning resources and critically analyze relevant published literature;
  •  Organize and supervise the desired managerial and leadership skills;
  •  Function as a productive member of team engaged in research and education.

 

3. Syllabus 

3.1. Theory 

 General and Cellular Physiology 

  •  General functional organization of human body  Cell-organelles and their functions.
  •  Cell to cell and local communications, Transport across cell membrane
  •  Body fluid compartments : Define and explain
  • Homeostasis : Definition, maintenance, control of internal environment, different regulatory systems in homeostasis.

 Principles of control systems :

 General characteristics and components of biological control system.

  •  Concept of negative and positive feedback
  •  Correction, error and feedback gain
  •  Hormonal control mechanism : Definition of hormones, receptors and target cells.  Role of hormones in homeostasis.
  •  Neural control of mechanism : Role in homeostasis.
  • Technology : Stimulus, excitability, conductivity, contractility, refractory period, chronaxie, rheobase, summation etc, 
  • Receptor  generator potential, properties and transduction
  •  Synapses ultrastructure, properties, synaptic plasticity, neurotransmitters and mode of transmission.

 Nerve and muscle physiology 

  •  Structure and functions of a neuron and neuroglia.
  •  Nerve fibre types, function and nerve injury.
  • Molecular basis of resting membrane and action potential, compound action potential, Recording.
  •  Structure and transmission across neuro-muscular junction.
  •  Neuro-muscular blocking agents.
  • Pathophysiology of Myasthenia gravis and other applied aspects of NM junction.
  •  Types and structure of muscle fibers.
  •  Action potential in different muscle types.
  •  Molecular basis of muscle contraction.
  •  Muscular changes during exercise.
  •  Energy sources and metabolism in muscle.
  •  Properties of excitable tissue.
  •  EMG.

 

 

 Autonomic nervous system 

  •  Anatomical organization of nervous system : 
  • Functional organization of nervous system : Divisions, distribution and functions.
  •  Higher control of autonomic nervous system.
  •  Physiological role of autonomic nervous system.  Pharmacology of autonomic nervous system.

 

 Blood,  reticulo-endothelial and immune system

 Respiratory system:

  •  Functional anatomy of respiratory system
  • Mechanics of breathing : Movements of thoracic cage during respiration, muscles involved and their nerve supply, intrapleural and pulmonary pressure and volume changes, pressure-volume inter-relationships, lung compliance – surfactant, airway resistance, work of breathing.
  • Spirometry, lung volumes & capacities : Definitions, normal values, significance and special features.
  • Pulmonary gas exchange : Alveolar-capillary membranes, diffusion capacities, partial pressure gradients and factors influencing diffusion of gases, measurement of diffusion capacity using carbon monoxide.
  •  Applied physiology  shunt and alveolar-capillary block
  •  Ventilation  perfusion ratio and its importance in respiratory diseases.

 Gas Transport 

  •  Oxygen transport – factors influencing the combination of haemoglobin with oxygen, oxygen dissociation curve- plotting, features, physiological advantage of its shape, factors affecting its shift and Bohr’s effect.
  •  Carbon dioxide transport – tissue uptake, carriage in blood and release at the lungs importance of red blood cell, chloride shift, role in acid base balance, Haldane effect.
  •  Regulation of respiration : Neural control – medulla, pons and vagus
  • Chemo-receptors:  peripheral and central, chemical and non-chemical influences on respiration, integrated responses.
  •  Respiration in unusual environments : High attitude hypoxia and space flight   Deep sea diving:  nitrogen narcosis, Hyperbaric oxygen and oxygen toxicity.
  • Abnormal breathing : Apnoea, hyperpnoea, tachypnoea, dyspnoea, Chynestokes breathing and Biot’s breathing- definition, features and physiological basis.
  •  Hypoxia, cyanosis.
  • Artificial respiration: Definition, types, principles, indications, advantages and disadvantages.
  •  Pulmonary function tests   Pulmonary abnormalities.

 

 Cardiovascular system :

  •  ontraction coupling (in brief)  All or none phenomenon, length-tension relationship.
  •  Frank-Starling Law, neural influences.
  •  Effect of ions and chemical on myocardial contractility.
  •  Cardiac cycle : Mechanical and electrical events,
  •  Heart as a mechanical pump : Design of systemic and pulmonary circulation.  Introduction of the venous pressure, flow and resistance.  Types of blood vessels and their functions.
  •  Properties of myocardial cells : Site of generation of cardiac impulse- pace maker tissue.
  •  Mechanisms of spontaneous generation of impulses.  Specialized conducting system and its importance  Electrical properties of working myocardial cells.
  •  Molecular basis of contraction and excitation
  •  pressure volume relationship  Electrocardiography : Definition, uses, principle, waves and their explanations.  ECG recording techniques
  •   Cardiac arrhythmias and their ECG interpretation 
  •  Cardiac output : Definition, normal values and variations, major determinants of cardiac output and regulation, Heart-lung preparation – measurement of cardiac output, Fick’s principle and its application, indicator dye methods of measurement, Regulation of heart rate and stroke volume.
  •  Haemodynamics : Definition of terms- pressure, flow, resistance, velocity etc.  Laminar and turbulent flow, Poiseuille law, factors affecting blood flow and resistance, critical closing pressure
  •   Various types of circulation, local regulation of blood flow to tissues.
  •  Arterial Blood Pressure : Definition, normal value, variations, measurement, mean arterial pressure (MAP) and its determinants.  
  •  Short term reflex control: baroreceptors and their significance.  Mechanism of reflex control and its limitations.
  •  Long term control: renal body fluid – pressure control mechanism, hypertension.
  •  Regional circulation : Coronary, cerebral, cutaneous, splanchnic, skeletal muscle and foetal. Normal values, special features and regulation.
  •  Cardiovascular changes during exercise.
  •   Cardiac failure, circulatory shock.

 

 Gastrointestinal system :

  •  Introduction to gastrointestinal Physiology : Functions of GI System – individual parts.  Innervation of the gut, regulation of GI functions – general overview.
  •   Oral Cavity : Mastication and digestion in mouth and its importance.  Salivary secretion: 
  •  mechanism, composition, functions and regulation.
  •  Physiology of deglutition : Definition, stages and neural control and applied aspects.
  •   Stomach : Overview of functions
  •  Physiology of gastric secretion – mechanism, composition, function and control.
  • Experimental procedures to elucidate and phases of gastric secretion.
  •  Gastric motility – characteristics and control, gastric emptying and antral

pump mechanism, peptic ulcer.

  •  Pancreatic secretions: Composition, mechanism, functions and control.
  •  Small intestine : Secretion, movement and control.
  •  Large intestine : Functions, secretions, movements.
  •  Gastrointestinal hormones and their role in secretomotor functions of the gut.

 Defaecation : Mechanism and control.

  •  Physiology of vomiting, diarrhoea, constipation.
  •  Digestion and absorption.
  •  Nutrition and vitamins.

 

 Hepatobiliary system :  Liver : Functions

  •  Entero hepatic circulation
  •  Bile formation, secretion, regulation and  jaundice
  •  Physiological basis of liver function tests
  • Gall bladder: Functions, Mechanism and regulation of gall bladder contraction, applied aspects and Oral cholecystography 

 

 The Body Fluids and Renal Physiology   Body fluid compartments and its regulation.

  •  Renal circulation.
  • Urine formation involving processes of filtration, tubular reabsorption, secretion and concentration.
  •  Water diuresis and osmotic diuresis.
  •  Regulation of acid base balance.
  •  Structure and function of a Juxta glomerular apparatus.
  • Renal mechanisms for the control of volume, blood pressure and ionic composition.
  •  Innervations of bladder, micturition and abnormalities of micturition.
  •  Artificial kidney, dialysis and renal transplantation. 
  •  Renal Function test.  Diuretics,  Renal failure

 Endocrinology 

  •  General Endocrinology
  •  Mechanism of action and Regulation of hormones
  • Physiological actions and applied aspects of pituitary gland, Thyroid gland, Parathyroid gland, Adrenal gland, Pancreas and hypothalamus, Growth Hormone.
  •  Estimation and assessment of Hormones.
  •  Pineal gland and local hormones.

 

 Reproductive System 

 Introduction : Sexual differentiation and development.  Male reproductive system :

  •  Primary and accessory organs and their functions.
  •  Spermatogenesis and its regulation
  •  Testosterone-         secretion,       transport,        metabolism,   mechanism    and physiological actions
  •  Control of testicular function – feedback mechanism and abnormalities.

 Female reproductive system :

 Physiology of menstrual cycle :

  •  Ovarian cycle, Uterine cycle,  vaginal and cervical cycle
  •  Physiology of ovulation and its detection  
  • Ovarian hormones – Estrogen and progesterone – physiological actions and mechanism of action
  •  Control of ovarian function:  feedback mechanism, menopause and abnormalities.
  •  Physiology of fertilization and implantation.
  • Physiology of pregnancy : Endocrine changes, foeto-placental unit, changes in mother during pregnancy, tests for pregnancy
  •  Physiology of parturition : Role of oxytocin  
  •  Physiology of lactation : Role of oxytocin and prolactin
  •  Infertility, contraception

 

  •  Growth, Development and Genetics 

  •  Growth and development : Definition

  •  Physical growth – prenatal & postnatal period, pubertal growth, skeletal age and physical maturity

  • Organ growth – differential growth of specific organs and tissues (Brain, head, lymphoid tissue, visceral and reproductive organs at various ages)  Growth spurts in human’s life-infancy and late puberty.

  • Growth rates in boys and girls, mental growth and factors influencing growth- genetic, nutritional and hormonal

  •  Disorders of normal growth
  •  Abnormalities of foetal and postnatal growth  Hereditary short stature.

 Physiology of ageing :

  •  Changes in various systems and mechanisms involved  Factors affecting ageing.

 Apoptosis.

  1.  Genetic control of protein synthesis, genetic code and regulation of gene expression, cell cycle and its regulation.

 Applied genetics

 

 Integumentary System 

  •  Skin : Functions
  •  Sweat glands : Types, secretion and functions.
  •  Thermoregulation : Mechanism, receptors
  •  Hypothalamic thermostat  Acclimatization
  •  Disorders of thermoregulation

 

 Metabolism 

  •  Carbohydrate, protein and lipid metabolism, Energetics and metabolic rate, obesity and starvation.

 

 Central Nervous System :

 Introduction : Organization of the nervous system  The structural and functional unit of nervous system.

 Neurons – types, functional components and morphology   Neuroglia – types, morphology, functions  and classification of nerves  Signal transmission in the nervous system : 

 Graded potential – definition, characteristics and physiological significance   Resting membrane potential – ionic basis  Action potential – definition  

  •  Ionic basis for electrical, chemical and excitability changes  Propagation, mechanism and factors influencing the same.
  •      Response of neurons and nerve fibers to injury   Types of injuries.
  •      Types of changes – Wallerian degeneration and regeneration   Factors influencing regeneration
  •  Microenvironment of the neuron: CSF-composition, formation & circulation, Blood brain barrier and its importance
  •  Synapse : Definition and types, structure, mechanism of transmission and properties
  •  Sensory receptors : Definition, classification and properties
  •  Reflexes : Definition and classification
  •  Reflex arc and stretch reflex
  •  Properties of reflexes and their clinical significance.
  • Somato-sensory system :
  •  Classification and characteristics of difference sensations  Sensory pathways and regulation at the higher level
  •  Physiology of pain including referred pain
  • Control of posture and movement 
  •  General Principles of organisation of motor control
  •  Effects of complete transection and hemisection of spinal cord  
  •  Descending pathways involved in motor control
  •  Corticospinal (pyramidal) system and  
  •  Corticobulbar (extraypyramidal) system
  •  Cortex, basal ganglia and cerebellum- motor control and their disorders
  •  Reticular formation : Definition, connections and functions
  •  Physiological basis of consciousness and sleep
  •  EEG : Evoked potentials and their clinical significance.
  •  Hypothalamus : Components, connections and functions
  •  Thalamus : Components, connections, functions, thalamic syndrome
  •  Limbic system : Components, connections and functions
  •  Frontal. Parietal, occipital and temporal lobe: components, connections, functions and effects of lesions  Higher cortical functions :
  •  Learning, memory, judgement, language and speech.

 

 Special Senses   Visual system :

  •  Structure of eye and overview of functions  
  •  Structure and function of cornea
  •  Aqueous humor – formation, circulation and drainage  
  •  Intraocular pressure and functions  
  •  Optics of vision – image forming mechanism
  •  Pupil and its functions  Light reflex and accommodation
  •  Binocular and monocular vision
  •  Common errors of refraction
  •  Visual acuity and visual fields – clinical importance  
  •  Ophthalmoscopy, retinoscopy and perimetry
  •  Photoreceptors – distribution, visual pigments and their functions
  •  Light and dark adaptation : photopic and scotopic vision
  • Visual pathway – transduction, transmission, synaptic modulation and visual cortex.
  •  Effects of transection of visual pathway at various levels.
  •  Eye movements – neurophysiological basis of fixation of gaze and conjugate movements.
  •  Physiology of colour vision – theories and electrophysiological aspects  Colour blindness – classification and tests.

 

 Auditory system:  

  •  Functional anatomy of ear and general properties of sound
  •  External ear – functions
  •  Middle ear – functions of tympanic membrane and ossicles,  
  •  Mechanism of sound transmission, impedance matching, function of
  • eustachian tube.
  •  Internal ear – structure and function of cochlea, sound transduction, electrical potentials from cochlea, pitch and intensity discrimination.
  •  Auditory pathway – receptive fields and tonotopic maps, binaural interactions, nerve pathway from the cochlea to the auditory cortex.
  •  Organization of auditory cortex and functions, sound localization
  •  Deafness : types, tests to diagnose deafness (practicals)  Audiometry and its clinical applications.
  •  The Vestibular System : Structure of labyrinth o Vestibular transduction – response to rotational and linear acceleration.
  • Central vestibular pathway 
  • Vestibulo-ocular reflex and its clinical importance o Clinical tests for vestibular integrity, disorders of labyrinth  The Olfactory System : Location of receptors and pathways, physiology of olfaction and disorders of olfactory sensation.

 The Gustatory System : Location of receptors and pathways,  physiology of gustation and disorders of gustatory sensation.

 

  •             Physiology of Sports,  Exercise, Yoga and Meditation

 

3.2. Practical 

 

 Haematology

  •  Study of compound microscope
  • To study the effect of isotonic, hypotonic and hypertonic solutions in human RBC’s.
  •  Estimation of Haemoglogin (Hb). 
  •  Heamocytometry.
  •  To determine the Total Leucocyte Count (TLC).
  •  To determine the Total Erythrocyte Count (RBC).
  •  Preparation of blood smear and identification of different cells present in blood.
  •  To determine the Differential Leucocyte Count (DLC).
  •  Determination of Arneth Count.
  •  Determination of Absolute Eosinophil Count.  Determination of ESR and PCV  Blood Indices.
  •  Reticulocyte Count.
  •  Platelet Count
  •  Determination of Specific Gravity of Blood.
  •  Determination of BT and CT.
  •  Determination of Osmotic Fragility of RBC’s.
  •  Determination of Blood Groups.
  •  Examination of Bone Marrow and study of various Haematopoetic cells. 

 

 Amphibian

  •  Study of apparatus used for amphibian experiments.
  •  Gastrocnemius muscle and Sciatic nerve preparation of frog.
  •  Recording of simple muscle twitch (SMT).
  •  To study the effect of temperature on SMT.
  •  To determine conduction velocity of nerve impulse.
  •  To study effect of load on SMT.
  •  Effect of increase in strength of stimulus on skeletal muscle contraction.
  •  Effect of two successive stimuli on SMT.
  •  Effect of increasing frequency of stimulus on SMT.
  •  Genesis of fatigue.
  •  Recording of normal cardiogram.
  •  To study the effect of temperature on normal cardiogram.
  •  To study properties of Heart muscle—Autorhythmicity and Conductivity.  To study the properties – Refractory Period and Extra Systole (ES) of Heart Muscle.
  •  To study All or None law and Staircase phenomenon.
  •  Effect of Vagosympathetic Trunk and White Crescentic Line on heart muscle.
  •  Effect of Vagal stimulation showing Vagal Escape.
  •  To study the effect of drugs – Adrenaline and Acetylcholine.
  •  To study the effect of  drugs – Nicotine and Atropine.
  •  Study of reflexes in Spinal and Decerebrate frog.
  •  Capillary circulation in frog (Frog Web).
  •  Perfusion of isolated heart of frog.
  •  To demonstrate the phenomenon of reciprocal innervation in frog.

 

 Human Experiments

  •  Phenomenon of human fatigue by Mosso’s Ergograph and Hand Grip Dynamometer.
  •  Clinical examination and recording of Arterial Pulse.
  •  Recording of Systemic Arterial BP and effect of posture and exercise.
  •   Recording of 12 lead ECG
  •  Plethysmography  (Measurement of Blood Flow).
  •  Stethography.
  •  Vitalography.
  •  Spirometry.
  •  Measurement of BMR.
  •  Cardiac Efficiency Tests.
  •  Perimetry.
  •  Auditory Function tests.
  •  Clinical examination of abdomen  Clinical examination of respiratory system.
  •  Clinical examination of CVS.
  •  Clinical examination of Nervous System.  Examination of Higher Functions  Examination of Cranial Nerves.
  •  Examination of Motor System.
  •  Examination of Sensory System.
  •  Reaction time (VRT & ART).
  •  Electroencephalogram (EEG).
  •  Autonomic Function Tests.
  •  Neuro – electrodiagnostic tests.
  •  Sensory and motor nerve conduction.
  •  Visual Evoked Potential (VEP).
  •  Auditory Evoked Potential (AEP).
  •  Critical Fusion Frequency (CFF).
  •  Cold Pressor Test (CPT).
  •  Galvanic Skin Resistance.

 

 Mammalian Experiments

  •  Record of movements of isolated Rabbit Intestine and effects of drugs and ions.
  •  Perfusion of mammalian heart by Langendorff’s Method and effect of drugs and ions.

 

Teaching Program 

4.1. General Principles 

  • Acquisition of practical competencies being the keystone of postgraduate medical education, postgraduate training is skills oriented.
  • Learning in postgraduate program is essentially self-directed and primarily emanating from clinical and academic work. The formal sessions are merely meant to supplement this core effort.

 

4.2. Teaching Sessions

  • Teaching sessions will be held in the form of seminars, journal clubs, microteaching, tutorials & discussions.

 

4.3. Teaching Schedule:

 

The suggested teaching schedule of the department is as follows :

 

1. Library day/Thesis work

Once a week

2. Seminar/Journal Club/Microteaching

Once a week 

3. Practical on systems 

Once a week 

4. Tutorial/Discussion/formal PG teaching

Once a week

5. Intradepartmental meet (with all the faculty and demonstrators   to discuss weekly teaching schedule and to discuss any of problem faced). 

 

Once a week

6. Central session (held in hospital auditorium regarding various topics like CPC, guest lectures, student seminars, grand round, sessions on basic sciences, biostatistics, research methodology, teaching methodology, health economics, medical ethics and legal issues). 

Once a week

 

  •  In addition, PG students also attend daily theory classes as per UG teaching schedule.

 

 

  1. Posting: 
  • The postgraduate student will rotate through allied clinical departments such as Biochemistry, Pathology, Transfusion Medicine, General Medicine, Pulmonary medicine, Cardiology, Neurology, Endocrinology and Nephrology.

 

  1. Thesis:
    1. Every candidate shall carry out work on an assigned research project under the guidance of a recognized Postgraduate teacher; the project shall be written and submitted in the form of a Thesis.

 

    1. Every candidate shall submit thesis plan to the university with in the time frame set by university.

 

    1. Thesis shall be submitted to the University six months before the commencement of theory examination i.e. for examination May/June session, 30th November of the proceeding year of examination and for November/December session 31st May of the year of examination.

 

    1. The student will identify a relevant question; (ii) conduct a critical review of literature; (iii) formulate a hypothesis; (iv) determine the most suitable study design; (v) state the objectives of the study; (vi) prepare a study protocol; (vii) undertake a study according to the protocol; (viii) analyze and interpret research data, and draw conclusions; (ix) write a research paper

 

 

1. Assessment

  • All the PG residents are to be assessed daily for their academic activities and also periodically.

 

7.1. General Principles 

  •  The assessment is valid, objective and reliable.
  •  It covers cognitive, psychomotor and affective domains.
  • Formative, continuing and summative (final) assessment is also conducted in theory as well as practicals / clinicals. In addition, thesis is also assessed separately.

 

7.2. Formative Assessment

  • The formative assessment is continuous as well as end-of-term.  The former is based on the feedback from the senior residents and the consultants concerned.  End-of-term assessment is held at the end of each semester (upto the 5th semester).  Formative assessment will not count towards pass/fail at the end of the program, but will provide feedback to the candidate.

 

7.3. Internal Assessment

  •          The performance of the Postgraduate student during the training period should be monitored throughout the course and duly recorded in the log books as evidence of the ability and daily work of the student. Marks should be allotted out of 100 as followed.

                          Sr. No.                      Items                                                         Marks

  1. Personal Attributes                                          20
  2. Practical Work                                                 20
  3. Academic activities                                          20
  4. End of term theory examination                     20
  5. End of term practical examination                 20         
  1. Personal attributes:
  •     Behavior and Emotional Stability: Dependable, disciplined, dedicated, stable in emergency situations shows positive approach.
  •     Motivation and Initiative: Takes on responsibility, innovative, enterprising, does not shirk duties or leave any work pending.
  •     Honesty and Integrity: Truthful, admits mistakes, does not cook up information, has ethical conduct, exhibits good moral values, loyal to the institution.  
  •  Interpersonal Skills and Leadership Quality: Gets on well with colleagues and paramedical staff, is respectful to seniors, has good communication skills. 

 

  1. Practical Work:
  •  Availability: Punctual, available continuously on duty, responds promptly on assignments and takes proper permission for leave. 
  •  Diligence: Dedicated, hardworking, does not shirk duties, leaves no work pending, does not sit idle, competent in practical work.
  •  Academic ability: Intelligent, shows sound knowledge and skills, participates adequately in academic activities, and performs well in oral presentation and departmental tests.  
  •  Performance: Proficient in presentations and discussion during academic sessions in the department.

 

  1. Academic Activity: Performance during presentation at Journal club/ Seminar/ Case discussion/ Stat meeting and other academic sessions. Proficiency in skills as mentioned in job responsibilities.  

 

  1. End of term theory examinations conducted at end of 1st, 2nd year and after 2 years 9 months.

 

  1. End of term practical/oral examinations after 2 years 9 months.

 

  •   Marks for personal attributes and work done should be given annually by all the consultants under whom the resident was posted during the year. Average of the three years should be put as the final marks out of 20.

 

  • Marks for academic activity should be given by the all consultants who have attended the session presented by the residents. 

 

  •  The Internal assessment should be presented to the Board of examiners for due consideration at the time of Final Examinations. 

 

7.4. Summative Assessment 

  •  Ratio of marks in theory and practicals will be equal.
  •  The pass percentage will be 50%.
  •  Candidate will have to pass theory and practical examinations separately.

 

A. Theory  Examination (Total =400)

               Paper            Title                                                                    Marks

                         

 

 

Paper 1 ; 

 

General Physiology                                    

100

Paper 2 :

Clinical Sciences related to Physiology 

100

            

 

 

Paper 3 :

Biophysics, Biochemistry & histology       

100

            

 

Related to systemic Physiology

 

Paper 4 :

Systemic Physiology including recent      

100

            

Advances                                                    

 

 

B. Practical Examination and Viva voce (Total =400)

                                                         

           Two  long exercises (mammalian/human)                                 200

           Two  short exercises (Hematology/microteaching)                     100

            Oral                                                                                           100

                                                                                     

  Job Responsibilities: 

For Teaching  

  •  Should be able to take a class using audiovisual aids right from blackboard & chalk to that with laptop & multimedia session.
  •  Should be able to make short lectures under senior teacher’s supervision.
  •  Should have learnt to make Power Point presentation.
  •  Should have learnt to make multiple-choice questions.
  •  Must attend all undergraduate theory and practical classes.  They must play an active role in table teaching in all practicals classes.

 

Job Responsibilities : 

For Teaching  

  •  Should be able to take a class using audiovisual aids right from blackboard & chalk to that with laptop & multimedia session.
  •  Should be able to make short lectures under senior teacher’s supervision.
  •  Should have learnt to make Power Point presentation.  Should have learnt to make multiple-choice questions.
  •  Must attend all undergraduate theory and practical classes.  They must play an active role in table teaching in all practicals classes.

 

For Research Work

  •  Should have skill to look up references from journals and present seminars.
  •  Should have computer skills.
  • Will be expected to be familiar with standards methods of preparing a bibliography and for preparing manuscripts and illustrations for publications.

 

Suggested Books –  Core Books:

  •  Text book of Medical Physiology by Guyton & Hall
  •  Review of Medical Physiology by William F. Ganong
  •  Understanding of Medical Physiology by Bijlani.

 

Reference Books:

  •  Human Physiology By Vander Sherman
  •  Physiological basis of medical practice by Best & Taylor.
  •  Bern & Levy Physiology 
  •  Human Anatomy and Physiology by Elaine N. Marieb.
  •  Principles of Medical Physiology by Sircar
  •  Text book of Medical Physiology by Indu Khurana  Fundamentals of Anatomy & Physiology by Martini.

 

Journals:

 Annual Review of Physiology.

 Indian journal of Physiology & Pharmacology.

 Journal of Applied Physiology.

 Physiological reviews.

 

9. Model Test Papers

 

Paper-I

General Physiology

Max. Marks:100

 

 

Time: 3 hrs

 

 

 

 

  • Attempt ALL questions
  • Answer each question & its parts in SEQUENTIAL ORDER
  • ALL questions carry equal marks
  • Illustrate your answer with SUITABLE DIAGRAMS

 

  1. Describe the transport of substances across cell membranes.
  2. Describe regulation of gene expression.       
  3. What are different types of membrane channels.  Describe the factors  regulating the gating of channels.  
  4. What is programmed cell death.  Describe the mechanism and features of  programmed cell death.
  5. Justify the term “Fluid Mosaic model” for the structure of a cell membrane.  
  6. Discuss in detail cellular and molecular mechanisms underlying biological  aging process.
  7. What are sources of stem cells.  How they are presented and write about their  clinical applications.
  8. Discuss role of lymphocytes in immunity.      
  9. Give an account of non-respiratory functions of lungs.   
  10. What is Hibernation.  Describe the physiological changes in hibernation.  

  

Paper-II

Clinical sciences as related to Physiology

Max. Marks:100

 

Time: 3 hrs

 

 

 

 

    • Attempt ALL questions
    • Answer each question & its parts in SEQUENTIAL ORDER
    • ALL questions carry equal marks
    • Illustrate your answer with SUITABLE DIAGRAMS

 

  1. Describe the synthesis and mechanism of action of thyroid hormones.
  2. Write physiological basis of prepotential in pacemaker tissue.       
  3. What is evoked potential.  Mention its clinical applications.            
  4. Define stretch reflex.  Describe the role of muscle spindle and  Comment upon  Babinski’s sign in UMN and LMN lesions.
  5. Explain cystometrogram in health and disease.   
  6. Describe the regulation of gastric emptying.  
  7. What are various methods of contraception and discuss their under lying  mechanism of action.
  8. Discuss the physiological basis of management of Diabetes Mellitus disease.  
  9. Describe the mechanism of pulmonary and cerebral oedema at high attitude.  
  10. Describe the pathophysiology of hypovolemic shock.  

 

 

 

Paper-III

Biophysics, Biochemistry & histology related to systemic physiology

Max. Marks:100

 

Time: 3 hrs

 

 

 

 

    • Attempt ALL questions
    • Answer each question & its parts in SEQUENTIAL ORDER
    • ALL questions carry equal marks
    • Illustrate your answer with SUITABLE DIAGRAMS

 

  1. Describe various pressure and volume changes in lungs & chest wall during normal respiratory cycle.
  2. Discuss pathophysiology of peptic ulcer.   
  3. Write physiological basis of use of digitalis in the treatment of heart disease.  
  4. Discuss sodium potassium pump.  Describe its role in genesis of resting  membrance potential.
  5. What is Poiseuille- Hagen formula.  Describe its clinical application in human  circulation.
  6. Describe mechanism of action of neurotransmitters in brain involved in  behaviour and emotions.
  7. What is referred pain? Describe physiological basis of referred pain.    
  8. Discuss the hormones involved in regulation of  glucose homeostasis.  
  9. Explain the factors affecting intraocular pressure.  Describe pathophysiology of  glaucoma.
  10. Describe the drugs affecting the transmission of impulse across  neuromuscular junction in skeletal muscle.

 

 

 

Paper-IV

Systemic Physiology including recent advances 

Max. Marks:100

 

Time: 3 hrs

 

 

 

 

    • Attempt ALL questions
    • Answer each question & its parts in SEQUENTIAL ORDER
    • ALL questions carry equal marks
    • Illustrate your answer with SUITABLE DIAGRAMS

 

  1. Discuss physiological basis and recent concepts of treatment of heart failure.
  2. What is glycemic index? Explain its clinical significance.  
  3. List various pulmonary function tests.  Explain the clinical significance of timed  vital capacity.
  4. Write about endogenous pain modulation.  Describe various chronic pain  syndromes.
  5. What are the types of decerebrate rigidity.  Discuss its physiological basis.  
  6. Explain indicators of ovulation.  What is their clinical importance.  
  7. What is Brown sequard syndrome.  What are its causes and explain its  features.
  8. Trace the path of auditory impulses in neural pathways from the cochlear hair  cells to auditory cortex. Discuss the function of auditory cortex.        
  9. Describe the digestion and absorption of fats.  Explain different causes of  steatrrhoea.
  10. What is respiratory quotient?  Describe the factors affecting respiratory  quotient.