Blood products WHO response

The WHO Action framework to advance universal access to safe, effective and quality-assured blood products 2020–2023 aims to provide strategic direction to global efforts to address present barriers to the safety and availability of blood products.

Working with Member States and partners, WHO aims to achieve universal access to safe, effective and quality assured blood products through the Framework’s 6 strategic objectives. The objectives focus on:

  1. Appropriately structured, well-coordinated and sustainably resourced national blood systems;
  2. Appropriate national frameworks of regulatory controls, national standards and quality assessment programmes;
  3. Functioning and efficiently managed blood services in all countries;
  4. Effective implementation of patient blood management to optimize clinical practice of transfusion;
  5. Effective surveillance, haemovigilance and pharmacovigilance, supported by comprehensive and accurate data collection systems;
  6. Partnerships, collaboration and information exchange to achieve key priorities and jointly address challenges and emerging threats at global, regional and national levels

Blood products

A blood product is any therapeutic substance derived from human blood, including whole blood and other blood components for transfusion, and plasma-derived medicinal products.

Medicinal (medical therapeutic) products derived from human donations of blood and plasma play a critical role in health care. Safe, effective and quality-assured blood products contribute to improving and saving millions of lives every year, as they:

  • address child mortality and maternal health;
  • dramatically improve the life expectancy and quality of life of patients suffering from life-threatening inherited disorders, such as haemophilia, thalassaemia and immune deficiency, and acquired conditions such as cancer and traumatic haemorrhage; and
  • support complex medical and surgical procedures, including transplantation.

An insufficient or unsafe blood supply for transfusion has a negative impact on the effectiveness of key health services and programmes to provide appropriate patient care in numerous acute and chronic conditions. Ensuring access of all patients who require transfusion to safe, effective and quality-assured blood products is a key component of an effective health system and vital for patient safety.