M.B.B.S. EXAMINATION PATHOLOGY (GENERAL PATHOLOGY & HAEMATOLOGY) PAPER-I

A forty year old man presented with history of persistent cough and evening rise of temperature over a period of 4 months, with associated loss of appetite and reduction in weight.  Examination revealed matted cervical lymph nodes.  An X ray chest done showed a small radiopaque focus in the apex of the upper lobe of right lung.

1. What is your diagnosis?
2. Describe in detail the pathogenesis of this disease.
3. Describe the microscopic features associated with this lesion.
4. Enumerate the complications associated with this condition.

1+4+3+2=10

WRITE SHORT NOTES ON:

5X4=20

Mechanism of wound healing by second intention

Type II hypersensitivity reaction

Characteristics of Benign and Malignant neoplasms

Laboratory investigations in a case of Hereditary spherocytosis

Pathogenesis of Septic Shock

WRITE BRIEFLY ON:

5X2=10

List any four types of necrosis with one example for each

Mention four inflammatory actions of Arachidonic acid metabolites

List four special stains to demonstrate amyloid

List four examples for edema due to reduced plasma osmotic pressure

Laboratory investigations in a case of Idiopathic Thrombocytopenic Purpura (ITP)